Monday, October 13, 2014

Med Reviews

By Trevor Shewfelt, Pharmacist at the Dauphin Clinic Pharmacy
“I can resist anything…..except temptation.”  Oscar Wilde may have hit the nail on the head when it comes to how important self control is.  I was dismayed when I heard how important it was that children be able to resist marshmallows.  There were these series of experiments done in the 1960’s by Walter Mischel.  Four year old children were offered a marshmallow.  They were told they could eat the one marshmallow whenever they wanted, but if they waited 15 minutes, they would get 2 marshmallows.  About 2/3’s of the kids ate the marshmallow right away and about 1/3 waited.  These kids have been followed for years.  They were checked on at age 13, at 18 and are still being followed today.  The 4 year olds who could delay gratification the longest were more successful in life than those who ate the marshmallow right away.  The kids with self control were thinner, had better grades, had better relationships, and were overall doing better at life.  This experiment concerned me so much because I’ve seen my son Eric eat 5 marshmallows at a friend’s bonfire before any of the other kids had choked down one.  When it comes to marshmallows, Eric resists temptation like Oscar Wilde.
It may seem counter intuitive that a four year old resisting marshmallows is a strong indicator of their future success.  Our society doesn’t celebrate self control, but when you think about it, self control is a very useful attribute.  It may also not be immediately obvious, but sitting down with your pharmacist to discuss your medications for 30-60 minutes can be very good for your health.  We call these extended interactions with a pharmacist a medication review.  In a community pharmacy, pharmacists spend most of our time making sure the right medication is in the right bottle for the right patient.  Then we explain how a patient can get the most use out of that medication.  I might tell them to take it with food, or to be careful because it might make them sleepy.  That is an over-simplification, but in general that is what I get paid to do.  In other provinces, pharmacists get paid to do more services for patients such as medication reviews.  And patients find these other services very valuable.  But you don’t have to take my word for it.  The Canadian Association of Retired People or CARP did a study.
Let’s take a step back.  What problems in the health care system did CARP think pharmacists could help with?  As the Canadian population ages, Canadians are living with multiple complex chronic illnesses like diabetes, heart disease and arthritis.  Multiple illnesses in one person often means multiple medications prescribed that person.  When a person has multiple medications, that increases the chances of medication non-adherence.  Medication non-adherence includes things like not taking medications properly, not filling prescriptions at all, missing refills, and skipping doses.  Non-adherence statistics in Canada are alarming.  It is estimated that 50% of patients with a chronic disease are non-adherent with their medications.  Medication non-adherence  leads to an estimated $7-9 billion of annual health care cost in Canada.  Even more frightening, it is estimated that 125.000 people die unnecessarily every year due to medication non-adherence.  One tool available to combat medication non-adherence is a medication review done by a pharmacist.
CARP and Shopper’s Drug Mart looked at Medication Reviews across Canada.  A medication review is an individualized, in-person meeting between a patient and a pharmacist.  It usually takes 30-60 minutes to perform.  During a medication review a pharmacist will discuss how to take each medication.  They will make sure each medication the patient is taking still matches up with a disease/condition the patient has.  For example a patient might not need a stomach acid medication for an ulcer that was healed last year.  The pharmacist will review what each medication is for including over the counter medications, vitamins and herbs.  If the patient is experiencing side effects the pharmacist will give them information about how to minimize them.  If any serious problems with the medications come up during the review, the pharmacist will consult with the patient’s doctor to solve them.
When CARP interviewed Canadians from BC, Alberta and Ontario who recently completed a medication review with their pharmacist, 85% of them were likely to make medication reviews a regular part of their health routine.  The main benefits cited were: preventing and managing adverse drug reactions, ensuring medications were being taken properly, improving medication effectiveness, improving pharmacist-patient-physician communication and having the pharmacist identifying additional clinical services that might benefit the patient.
The CARP study found medication reviews by pharmacists were paid for differently in different provinces.  Alberta had one of the most comprehensive medication review programs.  To have a medication review by a pharmacist paid for, an Albertan must have at least one chronic medical condition and be taking 3 or more prescription medications or be taking insulin.  Most other provinces pay at least something for patients to receive a medication review.  However 2 provinces don’t pay for medication reviews by pharmacists at all.  Those provinces are Manitoba and Quebec.
Recently I was listening to an interview with Walter Mischel, the marshmallow guy.  He said I interpreted the marshmallow results all wrong.  Just because Eric can’t resist a marshmallow (or five) he isn’t doomed.  The important thing is self control can be taught.  Mischel remembered a little girl in his test that ate the marshmallow right away.  He told her next time imagine the marshmallow was a picture.  Then she was able to resist the marshmallow for 15 minutes because in her words, “You can’t eat a picture.”  Maybe we can teach Eric to resist marshmallows.  Right after I learn how to resist beer and donuts.  Oscar Wilde was right.  Maybe I’ll just try to resist something other than temptation.
The information in this article is intended as a helpful guide only.  It is not intended to be used as a substitute for professional advice.  If you have any questions about your medications and what is right for you see your doctor, pharmacist or other health care professional.
We now have this and most other articles published in the Parkland Shopper on our Website.  Please visit us at www.dcp.ca
As always if you have any questions or concerns about these or other products, ask your pharmacist.

Wednesday, October 08, 2014

Toe Nail Fungus

By Trevor Shewfelt, Pharmacist at the Dauphin Clinic Pharmacy
The Watson Arts center put on their Beer and Cash fund raiser a couple weeks ago.  The beer from Half Pints Brewery in Winnipeg was to die for.  The food from Doug Morley was divine.  But the Johnny Cash’s we have in Dauphin stole the show.  It amazes me how much talent we have here in the Parkland.  I think my favorite Johnny Cash song isn’t one of his originals.  I think I like his cover of Nine Inch Nails, “Hurt” the best.
If you really did have nine inch long toe nails, fungus might be a problem for you.  Toe nails are specialized parts of the skin that protect the ends of our digits.  The nail grows out from the small area inside the white half moon by the cuticle.  It is estimated that 6.5% of Canadians have toe nail fungus.  It is more common in older people.  It is estimated that over 30% of people between the ages of 60 and 70 have toenail fungus.  People with nail problems like having a nail injury or psoriasis near the nail are more likely to get toe nail fungus.    Also people who wear footwear that don’t let the feet breathe, people with poor circulation to their feet, people with diabetes and people with compromised immune systems are more likely to get fungus.  The medical term for toe nail fungus is onychomycosis.  Onchomycosis is caused mainly by dermatophytes.
You can get infected toenails through contact with an infected person or through contact with an infected surface like a bathroom floor where the fungus is present.  It is common to get toenail fungus at the same time as you get athlete’s foot.
Fungus infected toenails look weird, but are not itchy or painful.  In the most common type of toe nail infection, the end and/or sides of the nail get thicken and yellow.  The infection can spread in all the way up to the cuticle and the nail matrix.  Crumbling yellow debris is usually seen under the nail edge.  We think of toenail fungus as just being ugly to look at.  However, there are some non-cosmetic problems that can result from a fungal infection.  The nail fungus can spread to other nails or even other parts of the body like the groin or scalp.  In diabetics, the thickening nail can add extra pressure to the toes and lead to ulcers or sores.  In extreme cases with diabetics, sores on the feet can lead to amputation, but that is rare.
What can be done if you have toenail fungus?  First you should have a doctor have a look at the nail.  There are other things besides fungus that can cause nail problems.  Once a definite diagnosis has been made, you and your doctor need to decide how you want it treated.  In some cases, the infected part of the nail can be removed.  Onychomyconsis can also be treated with medication.  There are both oral pills and topical medications to apply to the nail.
The two most common oral medications for toenail fungus are terbinafine (lamisil) and itraconazole (sporanox).  It is difficult to say which medications work the best because the studies about toenail fungus are very small and not that well done.  The studies usually talk about when the nail is fungus free.  A patient has to remember that even after the nail is fungus free, it will still take months and months for the nail to grow out and the yellow, thick, discolored areas to disappear.  Toe nails can take a year to grow back.
Terbinafine has to be taken every day for 3 months to cure toenail fungus.  Like all antifungals it can cause liver damage but the chances are remote.  Your doctor should test your liver function before you go on it and repeat the liver function test in about 6 weeks.  Depending on where I looked, I saw cure rates with terbinafine at about 46%.
Itraconazole is another antifungal oral medication, but it can be given as pulse therapy.  That means you take the pills everyday for a week and then take 3 weeks off.  You repeat this for 3 months.  This pulse therapy can be more convenient for many people.  Again there is the risk of liver damage and you doctor should check you out.  The cure rates for itraconazole I found were around 23%.
If you aren’t sure you want to get your liver function checked or have your toenail removed there are other options.  Ciclopirox (Penlac) looks like nail polish.  You apply it everyday and wipe off any excess about once a week with nail polish remover.  Again, it will need to be used for about 3 months.  The cure rate I found was about 7%.
There is a new prescription toe nail fungus nail polish on the market.  It is called Efinaconazole (Jublia).  Its cure rate is listed at 17%.
The Dauphin Clinic Pharmacy makes another anti-fungal nail polish.  For better or worse several of the doctor’s have dubbed it “Trevor’s Magic Nail Polish”.  It is made with the anti-fungal fluconazole.  There are no large clinical studies on it, so I have no cure rate to give you, but anecdotally some patients who used it found it worked well.  The big advantage of the fluconazole nail polish we compound over the commercial one is coverage.  If you go over your pharmacare deductible our compounded nail polish is covered while the commercial one is not.
Which ever nail fungus treatment you choose there are some things you can do on you own to help your toenails.  Keep your nails short, dry, and clean.  Keep your feet dry – make sure your feet (including between your toes) are completely dry before putting on shoes and socks.  Wear absorbent cotton socks , and change them at least once a day.  Wear proper fitting shoes and rotate shoes to allow them to dry out between uses.  Don’t go barefoot in damp public places like public showers – wear shower shoes.  People with nail fungus shouldn’t share shoes, socks or nail clippers with others.  If you have diabetes, make sure your blood sugar is under control.  As mentioned we don’t want people with diabetes having their toe nail fungus causing sores and ulcers.
“You could have it all…My Empire of Dirt.  I will let you down.  I will make you hurt.”  Johnny Cash’s cover is better than the Nine Inch Nails original.  Nine Inch nails won’t help your foot health either.  So dry those feet and trim those toe nails.  Don’t let toe nail fungus make you hurt.  Look after your feet and your feet will look after you.
The information in this article is intended as a helpful guide only.  It is not intended to be used as a substitute for professional advice.  If you have any questions about your medications and what is right for you see your doctor, pharmacist or other health care professional.

We now have this and most other articles published in the Parkland Shopper on our Website.  Please visit us at www.dcp.ca
 As always if you have any questions or concerns about these or other products, ask your pharmacist.

 Hurt – Johnny Cash www.youtube.com/watch?v=Bp4UI_FxGLE
Hurt – Nine Inch Nails www.youtube.com/watch?v=AvJKVKglIRs